Ildong Pharmaceutical Group's anti-cancer drug development company Ildong Pharmaceutical Group annou.. - MK

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Ildong Pharmaceutical Group's anti-cancer drug development company Ildong Pharmaceutical Group announced on the 12th that it has signed an agreement with Aptis, a company specializing in antibody-drug conjugates (ADC) platforms of Dong-A Socio Group, to jointly develop next-generation dual payload ADC.

Double payload ADC is a drug that inhibits and kills cancer cells by combining payloads with two or more different mechanisms of action with one antibody.

Regarding this agreement, the company explained, "We have joined forces to develop precise treatments that can overcome the limitations of existing single payload ADC, such as tumor heterogeneity and anticancer drug resistance problems."

Under the agreement, the two sides plan to develop ADCs that maximize treatment efficacy and safety by utilizing IDENS' next-generation PARP-inhibiting target anticancer drug "Venadaparib" and APTIS' positional selective bonding technology "AbClick."

The two companies plan to focus their capabilities on developing innovative anticancer drugs that can be applied to various carcinomas based on research data and results secured in the future.

"This project is a groundbreaking attempt to expand PARP inhibitors to ADC payloads based on clinical data from combination therapy," said Lee Won-sik, CEO of IDans. "It will serve as an opportunity to secure differentiated candidates and technological competitiveness in the global ADC market."

Han Tae-dong, CEO of Aptis, also said, "We will combine ADC-related source technologies and platforms and promising anticancer drug pipelines of Aptis to create synergies," adding, "We hope it will be a turning point in opening a new chapter in the development of next-generation dual payload ADC."

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